An Evening on the Fireside with David

An Evening on the Fireside with David 14.

Hello and welcome another exciting issue of the Evening on the Fireside with David. I'll be talking about another http://www.curiousread.com article entitled
Scientists stop the ageing process
The title is slightly misleading (when are titles not?), but I've extremely loosely followed the few things scientists have to do in order to effectively stop aging. This one was a new one for me. Here is an excerpt on what they were working on.

"As people age their cells become less efficient at getting rid of damaged protein resulting in a build-up of toxic material that is especially pronounced in Alzheimer's, Parkinson's and other neurodegenerative disorders."
And a little bit more in depth little thing here.

"If the body's ability to dispose of cell debris within the cell were enhanced across a wider range of tissues, she says, it could extend life as well.
In healthy organisms, a surveillance system inside cells called chaperone-mediated autophagy (..:namespace prefix = st1 ns = "urn:schemas-microsoft-com:office:smarttags" />CMA) locates, digests and destroys damaged proteins.
Specialised molecules, the "chaperones", ferry the harmful material to membrane-bound sacs of enzymes within the cells known as lysosomes.
Once the cargo has been "docked", a receptor molecule transfers the protein into the sac, where it is rapidly digested.
With age, these receptors stop working as well, resulting in a dangerous build-up of faulty proteins that has been linked, in the liver, to insulin resistance as well as the inability to metabolise sugar, fats or alcohol.
The same breakdown of the cell's cleaning machinery can also impair the liver's ability to remove the toxic build-up of drugs at a stage in life when medication is often part of daily diet."
But at the end, the toss this in.
"It is also possible that the same kind of "cellular clearance" can be achieved through diet, she says.
Research over the past decade has shown that restricted calorie intake in animals, including mammals, significantly enhances longevity.
"My ideal intervention in the future would be a better diet rather than a pill," she says."
So, a very cool little article and a kick-ass breakthrough I suppose. Have a good weekend folks. I'm going to try to get the official episode 1 of my podcast up with content, tentively named The Sect of ZAP: The TUT Origins.